Balchem – NiaShure™ Precision Release Niacin

Target Animals: Dairy Cattle

Rumen-Protected Niacin for Heat Stress Relief and Ketosis Management

Reduces heat stress by enhancing vasodilation, sweating, and internal cooling.

Helps stabilize cells and protect against heat damage at the molecular level.

Mitigates prepartum ketosis risk by lowering NEFA levels and reducing fat mobilization.

Delivers 8x more bioavailable niacin to the small intestine than raw niacin.

Balchem – NiaShure™ Precision Release Niacin technical details ​

NiaShure™ Precision Release Niacin is an advanced rumen-protected niacin designed to improve dairy cow comfort, health, and productivity during periods of heat stress and metabolic challenge. Using Balchem’s proprietary encapsulation technology, NiaShure™ protects niacin from microbial degradation in the rumen—allowing a controlled release further along the digestive tract where absorption is maximized.

Up to 95% of unprotected niacin can degrade in the rumen. NiaShure™ overcomes this barrier, providing up to 85% rumen stability and delivering eight times more bioavailable niacin to the small intestine than raw forms.

NiaShure™ works quickly, requiring no adaptation period—simply add it to the ration during heat stress events and remove it once temperatures normalize. This makes it a true precision feeding tool for modern dairy nutrition.


How NiaShure™ Works

1. Reduce Heat Stress – Through Vasodilation

Niacin promotes vasodilation, expanding blood vessels and increasing blood flow to the skin surface. This process enhances heat dissipation and helps cows maintain a lower core body temperature.

  • Increases peripheral circulation for better heat release.
  • Promotes sweating to reduce internal temperature.
  • Proven to lower core body temperature by ~1°F during thermal stress.

2. Reduce Heat Stress – Through Cellular Stabilization

Studies from the University of Arizona show that niacin increases heat shock protein (HSP) production in dairy cows. These proteins repair and stabilize cells damaged by heat, improving cellular resilience and maintaining normal metabolic function.

  • Increases production of protective heat shock proteins (HSP70).
  • Enhances cell survival and function under high temperature conditions.

3. Mitigate Ketosis

In overweight or metabolically stressed cows, NiaShure™ helps lower blood NEFA levels prepartum by reducing fat mobilization from body stores. This limits fat accumulation in the liver and reduces ketosis risk.

  • Acts as a potent anti-lipolytic agent, reducing NEFA surges before calving.
  • Lowers prepartum blood lipid mobilization for improved metabolic stability.

Key Benefits

  • Keeps cows cooler from the inside by improving internal heat regulation.
  • Reduces environmental and metabolic heat stress impacts on milk yield.
  • Improves reproductive efficiency during summer heat periods.
  • Enhances energy balance and supports healthy transitions.

Scientific Backing

Multiple trials from the University of Arizona confirm that supplemental NiaShure™ improves dairy cow thermoregulation, reduces core temperature, and supports cell-level protection against heat damage—all while maintaining milk yield and reproductive performance.


Balchem – NiaShure™ gives producers a powerful, research-proven solution to combat heat stress and metabolic challenges — improving comfort, productivity, and herd health even under extreme conditions.

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